ICEES KG

Homepage URL: https://robokop.renci.org/api-docs/docs/automat/icees-kg

Description: The Integrated Clinical and Environmental Exposures Service (ICEES) Knowledge Graph (KG) is an open service that exposes clinical data (i.e., electronic health records, clinical study data) that have been integrated at the patient level with public exposures data (e.g., airborne pollutants, major roadways/highways, concentrated animal feeding operations, landfills), with pairwise positive and negative correlations between feature variables reported on edges.

Example edge (interpretation): ICEES KG shows that cystic fibrosis is correlated with average daily exposure to PM2.5, with a Chi Square statistic of 19.55 and a P value of 0.0006 (N = 1296) in a cohort of patients from UNC Health in year 2010.

Data sources: ICEES KG exposes data from varied sources, including electronic health record data, clinical study data, and environmental exposures data.

Key methodologic metrics: ICEES KG provides pairwise correlations between feature variables, with Chi Square statistic, Chi Square P value, odds ratio, log odds ratios, 95% confidence interval for log odds ratio, Fisher’s exact P value for log odds ratio, and sample size.

Regulatory requirement(s) and/or licensing restriction(s): Service is compliant with all federal and institutional regulations.

Additional links:

• https://github.com/NCATSTranslator/Translator-All/wiki/ICEES