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Colleen Xu edited this page Feb 15, 2024 · 1 revision

Overview

Multiple BioThings APIs are created and maintained by the Service Provider team to make knowledge-source data accessible through high-performance BioThings APIs. All knowledge-source data is "open-source", but please look at the licensing information for each individual knowledge-source for full details.

Each knowledge-source's data is:

  • cleaned up and processed. The data is often organized by unique entity (ex: by individual gene) or by unique association (ex: unique combo of subject-predicate-object)
  • put into individual APIs and hosted at https://biothings.transltr.io/

Access / Interfaces

These BioThings APIs do not comply to the TRAPI standard. More information on how to query each API directly is provided in their SmartAPI registrations. Their individual pages in https://biothings.transltr.io/ also have examples of how to query each API directly.

However, in collaboration with the Exploring Agent team, these BioThings APIs are accessible as TRAPI KP services through:

In these situations, BioThings Explorer acts as a "TRAPI wrapper/transformer" that queries the BioThings APIs and processes their responses into knowledge-graphs that follow TRAPI and biolink-model standards (for node categories, edge predicates, etc).

Knowledge Sources

This list includes the server url for each BioThings API, the SmartAPI registration, and the Translator wiki page for the knowledge source.

API Name Link to API SmartAPI Registration Knowledge Source
BioThings AGR https://biothings.transltr.io/agr Link AGR
BioThings BindingDB https://biothings.transltr.io/bindingdb Link BindingDB
BioThings BioPlanet Pathway-Disease https://biothings.transltr.io/bioplanet_pathway_disease Link BioPlanet
BioThings BioPlanet Pathway-Gene https://biothings.transltr.io/bioplanet_pathway_gene Link BioPlanet
BioThings DDInter https://biothings.transltr.io/ddinter Link DDInter
BioThings DGIdb https://biothings.transltr.io/dgidb Link DGIdb
BioThings DISEASES https://biothings.ncats.io/DISEASES Link DISEASES
BioThings EBIgene2phenotype https://biothings.transltr.io/ebigene2phenotype Link EBIgene2phenotype
BioThings Gene Ontology Biological Process https://biothings.transltr.io/go_bp Link GO
BioThings Gene Ontology Cellular Component https://biothings.transltr.io/go_cc Link GO
BioThings Gene Ontology Molecular Activity https://biothings.transltr.io/go_mf Link GO
BioThings GTRx https://biothings.transltr.io/gtrx Link GTRx
BioThings Human Phenotype Ontology https://biothings.transltr.io/hpo Link HPO
BioThings iDISK https://biothings.transltr.io/idisk Link iDISK
BioThings InnateDB https://biothings.transltr.io/innatedb Link InnateDB
BioThings MGIgene2phenotype https://biothings.transltr.io/mgigene2phenotype Link MGI
BioThings PFOCR https://biothings.transltr.io/pfocr Link PFOCR
BioThings RARe-SOURCE https://biothings.transltr.io/rare_source Link RARe-SOURCE
BioThings Rhea https://biothings.transltr.io/rhea Link Rhea
BioThings SEMMEDDB https://biothings.transltr.io/semmeddb Link SemMedDB
BioThings SuppKG https://biothings.transltr.io/suppkg Link SuppKG
BioThings Therapeutic Target Database (TTD) https://biothings.transltr.io/ttd Link TTD
BioThings UBERON Ontology https://biothings.transltr.io/uberon Link UBERON

Source Code / Repo for issues

External Documentation

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