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Mead_et_al_NatBME_2022

Code and analyses for:

Mead, B.E., Hattori, K., Levy, L. et al. Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nat. Biomed. Eng 6, 476–494 (2022). https://doi.org/10.1038/s41551-022-00863-9

Includes analysis pipeline for Primary and Secondary screening, and single-cell RNA-seq analysis scripts for processed DGEs (data available at Broad Institute single cell portal)

Murine: https://singlecell.broadinstitute.org/single_cell/study/SCP1547/murine-small-intestinal-organoid-xpo1-inhibition

Human: https://singlecell.broadinstitute.org/single_cell/study/SCP1318/human-small-intestinal-organoid-xpo1-inhibition

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Code and analyses for Mead et al Nature BME 2022

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