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Genomic context annotation for any set of genomic ranges using UCSC Genome Browser tables

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goldmine: Genome context annotation in R or from the command line

About

  • Obtains data by direct downloading and updating of a local mirror of select UCSC Genome Browser annotation tables
  • R package contains functions to assess genomic context of any given set of genomic ranges by performing overlaps with regions of annotated genomic features and produce long, short, and plot outputs
  • Also contains a script that allows annotation of a flat file from the command line, without needing the user to code in R

Development Progress

  • getUCSCTable has been implemented which supports downloading and loading of any UCSC table from any UCSC genome into R, and can optionally sync a local cache of these tables

Installation

From R:

library(devtools)
install_github("goldmine", user="bluecranium")

Usage

Example: Loading knownGene on the fly to a data.frame

library(goldmine)
knownGene <- getUCSCTable("knownGene","hg19")

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Genomic context annotation for any set of genomic ranges using UCSC Genome Browser tables

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  • R 99.6%
  • Python 0.4%