refactoring and optimizations in annotations #4218

Job	Run time
MacOS (DNA, Debug, x64)	18m 15s
MacOS (DNA, Debug, arm64)	18m 32s
MacOS (DNA, Release, x64)	18m 32s
MacOS (DNA, Release, arm64)	18m 31s
Linux (DNA, Debug, g++-8)	11m 56s
Linux (DNA, Debug, g++-9)	12m 12s
Linux (DNA, Debug, g++-10)	12m 13s
Linux (DNA, Debug, g++-11)	12m 11s
Linux (DNA, Release, g++-8)	12m 12s
Linux (DNA, Release, g++-9)	12m 10s
Linux (DNA, Release, g++-10)	12m 11s
Linux (DNA, Release, g++-11)	12m 11s
Linux (DNA, Release, g++-11, static, noAVX)	12m 11s
Linux (DNA, Release, g++-11, static)	12m 12s
Linux (Protein, Debug, g++-8)	12m 12s
Linux (Protein, Debug, g++-10)	12m 10s
Linux (Protein, Debug, g++-11)	12m 11s
Linux (Protein, Release, g++-8)	12m 9s
Linux (Protein, Release, g++-10)	12m 11s
Linux (Protein, Release, g++-11)	12m 10s
Linux (Protein, Release, g++-11, static, noAVX)	12m 11s
Linux (Protein, Release, g++-11, static)	12m 10s
Test metagraph workflows	0s
Create Release	0s
Build-and-Push-Docker	0s
	4h 52m 53s

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