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# RustSASA | ||
![GitHub Actions Workflow Status](https://img.shields.io/github/actions/workflow/status/maxall41/RustSASA/rust.yml) | ||
![Crates.io Downloads (recent)](https://img.shields.io/crates/dr/rust-sasa) | ||
![Crates.io License](https://img.shields.io/crates/l/rust-sasa) | ||
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RustSASA is a Rust library for computing the absolute solvent accessible surface area (ASA/SASA) of each atom in a given protein structure using the Shrake-Rupley algorithm[1]. | ||
## RustSASA Implementation vs Biopython Implementation | ||
Benchmarks were performed on an M2 Apple Mac with 8GB of RAM and 8 Cores with the protein AF-A0A2K5XT84-F1 (AlphaFold). | ||
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Biopython: ~150ms | ||
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RustSasa: ~50ms | ||
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## Documentation: | ||
See https://docs.rs/rust-sasa/latest/rust_sasa/ | ||
## Citations: | ||
1: Shrake A, Rupley JA. Environment and exposure to solvent of protein atoms. Lysozyme and insulin. J Mol Biol. 1973 Sep 15;79(2):351-71. doi: 10.1016/0022-2836(73)90011-9. PMID: 4760134. |