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Post-COVID Knowledge Graph (KG) 🦠🔍📊

Welcome to the Post-COVID Knowledge Graph (KG) repository! 🌟

About ℹ️

The Post-COVID Knowledge Graph project aims to comprehensively map the molecular mechanisms, gene-disease associations, drug-target interactions, and omics data from patients, providing insights into post-COVID-19 syndrome and potential treatment options. Utilizing resources like the COVID-19 Disease Map,pyBiodataFuse python package and different drug repurposing algorithms, this project seeks to integrate information from various sources to achieve a thorough understanding of the disease and its potential treatments.

methods

Projects 🛠️

This repository hosts several parts related to the Post-COVID Knowledge Graph. Each part addresses different aspects of post-COVID-19 syndrome; KG construction, data exploration and visualization, and algorithm implementation. 📑📊💻

Project 1: Knowledge Graph Construction 🧩

Description: In this project, we build the Post-COVID Knowledge Graph using transcriptomic data and the pyBiodataFuse python package to extract relevant associations between genes, drugs, diseases, gene ontologies, locations and pathways. 🧠🖥️

Project 2: Data Exploration and Visualization 📊👀

Description: Gene set enrichment analysis, over-representation analysis, PPI networks in Cytoscape.

Project 3: Drug Repurposing Algorithm 💊🔄

Description: This part involves selecting different algorithms, visualising them, and comparing their functionality and results.

Getting Started 🚀

To get started with the Post-COVID KG project, follow these steps:

  1. Clone the repository:
    git clone https://github.com/macsbio/post-covid-kg.git
    

License 📝

This project is licensed under the MIT License.

Contact 📧

For any inquiries or suggestions regarding the Post-COVID Knowledge Graph project, feel free to reach out to the project maintainer:

Alejandro Adriaque Lozano ✉️