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Update gorule-0000002.md
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Clarified gorule-0000002
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pgaudet authored Jul 27, 2023
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Expand Up @@ -21,14 +21,13 @@ examples:
format: gaf
input: "PomBase SPAC23H4.18c rbx1 GO:0005515 PMID:12167173 IPI PomBase:SPBC1718.01 F SCF complex, Cul4-RING and CLRC ubiquitin ligase ligase E3 subunit Rbx1 pip1 protein NCBITaxon:4896 20041130 PomBase"
---
No direct annotations to protein binding ; GO:0005515 can contain the qualifier 'NOT' in GAF 2.2 Column 4 or GPAD 2.0 Column 2.

Even if an identifier is available in the 'with' column, a qualifier
only informs on the GO term, it cannot instruct users to restrict the
annotation to just the protein identified in the 'with', therefore an
annotation applying protein binding ; GO:0005515 with the not qualifier
implies that the annotated protein cannot bind anything.

This is such a wide-reaching statement that few curators would want to
make.
implies that the annotated protein cannot bind anything, which is unlikely to be correct.

This rule *only* applies to GO:0005515; children of this term can be
qualified with not, as further information on the type of binding is
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