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Obsoleted multiple terms under TCA cycle enzyme complex, #26882.
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raymond91105 committed Feb 3, 2024
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50 changes: 27 additions & 23 deletions src/ontology/go-edit.obo
Original file line number Diff line number Diff line change
Expand Up @@ -56644,12 +56644,13 @@ relationship: part_of GO:0005737 ! cytoplasm

[Term]
id: GO:0005962
name: mitochondrial isocitrate dehydrogenase complex (NAD+)
name: obsolete mitochondrial isocitrate dehydrogenase complex (NAD+)
namespace: cellular_component
def: "Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu]
comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'isocitrate dehydrogenase (NAD+) activity ; GO:0004449'.
intersection_of: GO:0045242 ! isocitrate dehydrogenase complex (NAD+)
intersection_of: part_of GO:0005739 ! mitochondrion
def: "OBSOLETE. Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu]
comment: The reason for obsoletion is that this term is unnecessarily taxon-specific.
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26882" xsd:anyURI
is_obsolete: true
replaced_by: GO:0045242

[Term]
id: GO:0005963
Expand Down Expand Up @@ -156407,13 +156408,14 @@ relationship: part_of GO:0031966 ! mitochondrial membrane

[Term]
id: GO:0030062
name: mitochondrial tricarboxylic acid cycle enzyme complex
name: obsolete mitochondrial tricarboxylic acid cycle enzyme complex
namespace: cellular_component
def: "Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu]
def: "OBSOLETE. Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu]
comment: The reason for obsoletion is that this term is unnecessarily taxon-specific.
synonym: "TCA cycle enzyme complex" BROAD []
intersection_of: GO:0045239 ! tricarboxylic acid cycle enzyme complex
intersection_of: part_of GO:0005739 ! mitochondrion
relationship: part_of GO:0005759 ! mitochondrial matrix
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26882" xsd:anyURI
is_obsolete: true
replaced_by: GO:0045239

[Term]
id: GO:0030063
Expand Down Expand Up @@ -262763,13 +262765,14 @@ intersection_of: capable_of GO:0004449 ! isocitrate dehydrogenase (NAD+) activit

[Term]
id: GO:0045243
name: cytosolic isocitrate dehydrogenase complex (NAD+)
name: obsolete cytosolic isocitrate dehydrogenase complex (NAD+)
namespace: cellular_component
def: "Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu]
def: "OBSOLETE. Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity." [GOC:mah, GOC:mtg_sensu]
comment: The reason for obsoletion is that this term is unnecessarily taxon-specific.
synonym: "isocitrate dehydrogenase complex (NAD+)" BROAD []
is_a: GO:0045246 ! cytosolic tricarboxylic acid cycle enzyme complex
intersection_of: GO:0045242 ! isocitrate dehydrogenase complex (NAD+)
intersection_of: part_of GO:0005829 ! cytosol
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26882" xsd:anyURI
is_obsolete: true
replaced_by: GO:0045242

[Term]
id: GO:0045244
Expand All @@ -262779,21 +262782,20 @@ alt_id: GO:0008325
alt_id: GO:0045245
def: "A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP." [GOC:jl, PMID:27487822]
synonym: "succinyl-CoA synthetase, GDP-forming" EXACT [CORUM:392]
is_a: GO:0030062 ! mitochondrial tricarboxylic acid cycle enzyme complex
is_a: GO:0042709 ! succinate-CoA ligase complex
intersection_of: GO:0030062 ! mitochondrial tricarboxylic acid cycle enzyme complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0004776 ! succinate-CoA ligase (GDP-forming) activity
intersection_of: part_of GO:0005739 ! mitochondrion

[Term]
id: GO:0045246
name: cytosolic tricarboxylic acid cycle enzyme complex
name: obsolete cytosolic tricarboxylic acid cycle enzyme complex
namespace: cellular_component
def: "Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu]
def: "OBSOLETE. Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle." [GOC:mah, GOC:mtg_sensu]
comment: The reason for obsoletion is that this term is unnecessarily taxon-specific.
synonym: "TCA cycle enzyme complex" BROAD []
synonym: "tricarboxylic acid cycle enzyme complex" BROAD []
is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex
relationship: part_of GO:0005829 ! cytosol
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26882" xsd:anyURI
is_obsolete: true
replaced_by: GO:0045239

[Term]
id: GO:0045247
Expand Down Expand Up @@ -262855,6 +262857,7 @@ synonym: "alpha-ketoglutarate dehydrogenase complex" EXACT []
synonym: "dihydrolipoamide S-succinyltransferase complex" EXACT []
synonym: "KGDHC" EXACT []
xref: Wikipedia:Oxoglutarate_dehydrogenase_complex
is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex
is_a: GO:0045240 ! alpha-ketoacid dehydrogenase complex
intersection_of: GO:0032991 ! protein-containing complex
intersection_of: capable_of GO:0034602 ! oxoglutarate dehydrogenase (NAD+) activity
Expand Down Expand Up @@ -262893,6 +262896,7 @@ id: GO:0045257
name: succinate dehydrogenase complex (ubiquinone)
namespace: cellular_component
def: "The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration." [GOC:kd, ISBN:0198547684]
is_a: GO:0045239 ! tricarboxylic acid cycle enzyme complex
is_a: GO:0045281 ! succinate dehydrogenase complex
intersection_of: GO:0045281 ! succinate dehydrogenase complex
intersection_of: capable_of GO:0008177 ! succinate dehydrogenase (quinone) activity
Expand Down
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Here's a diff of how these changes impact the classified ontology:

Ontology comparison

Left

  • Ontology IRI: http://purl.obolibrary.org/obo/go.owl
  • Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-02-03/go.owl
  • Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-master.owl/reasoned.owl

Right

  • Ontology IRI: http://purl.obolibrary.org/obo/go.owl
  • Version IRI: http://purl.obolibrary.org/obo/go/releases/2024-02-03/go.owl
  • Loaded from: file:/__w/go-ontology/go-ontology/src/ontology/../../reasoned-pr.owl/reasoned.owl

Ontology imports

Ontology annotations

cytosolic isocitrate dehydrogenase complex (NAD+) http://purl.obolibrary.org/obo/GO_0045243

Removed

Added

cytosolic tricarboxylic acid cycle enzyme complex http://purl.obolibrary.org/obo/GO_0045246

Removed

Added

mitochondrial isocitrate dehydrogenase complex (NAD+) http://purl.obolibrary.org/obo/GO_0005962

Removed

Added

mitochondrial tricarboxylic acid cycle enzyme complex http://purl.obolibrary.org/obo/GO_0030062

Removed

Added

oxoglutarate dehydrogenase complex http://purl.obolibrary.org/obo/GO_0045252

Added

succinate dehydrogenase complex (ubiquinone) http://purl.obolibrary.org/obo/GO_0045257

Added

succinate-CoA ligase complex (GDP-forming) http://purl.obolibrary.org/obo/GO_0045244

Removed

Added

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