A pipeline for identifying the most notable druggable interactors of a target within a e(BE:L) generated Knowledge Graph. This feature will be integrated into the e(BE:L) package in the future.
$ pip install drugintfinder
Finding the direct causal interactors of the phosphorylated MAPT protein:
$ dif find MAPT -n protein -e causal -m pho
Finding the direct causal interactors of the phosphorylated MAPT protein which are druggable:
$ dif find MAPT -n protein -e causal -m pho -d
Creating a table of various parameters for each interactor by which to rank them:
$ dif rank MAPT -m pho
The Druggable Interactor finder is a resource developed in an academic capacity funded by the MAVO project and thus comes with no warranty or guarantee of maintenance or support.