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Project to generate phenotype opposite_of relationships and investigate the effect on ontology-based algorithms

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drseb/phenopposites

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afca584 · Oct 4, 2017

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phenopposites

Project to generate phenotype opposite_of relationships in PATO, MPO and HPO. We also investigate the effect including this reltionship in ontology-based algorithms like semantic similarity.

  • lexically derived - these were obtained by looking for pairs of labels that differ according to an antonym pair (see antonyms file)
  • logically derived - using the OWL definitions in HP/MP, and the is opposite of relationships in PATO. See for example increased height.

publication

Currently there is only a preprint version for this project. See http://biorxiv.org/content/early/2017/02/16/108977