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Merge pull request #25 from ExposuresProvider/minerva
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balhoff authored Feb 13, 2024
2 parents bb88151 + a3498b5 commit eeda3bb
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Showing 26 changed files with 2,267 additions and 790 deletions.
46 changes: 22 additions & 24 deletions models/AOP_10.ttl
Original file line number Diff line number Diff line change
Expand Up @@ -22,7 +22,7 @@
<http://purl.obolibrary.org/obo/RO_0002213> <http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/GO_0060079> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://purl.obolibrary.org/obo/GO_0007268> a <http://www.w3.org/2002/07/owl#Class> .

Expand All @@ -31,7 +31,7 @@
<http://purl.obolibrary.org/obo/RO_0002213> <http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/GO_0007268> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://purl.obolibrary.org/obo/CHEBI_17996> a <http://www.w3.org/2002/07/owl#Class> .

Expand All @@ -54,61 +54,61 @@
<http://purl.obolibrary.org/obo/RO_0002352> <http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/CHEBI_17996> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> <http://geneontology.org/lego/hint/layout/x> "460.75"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "1465.9999542236328"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0002213> <http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/GO_0022851> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> <http://geneontology.org/lego/hint/layout/x> "665.625"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "1606.25"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0002212> <http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/GO_0050811> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-1> <http://geneontology.org/lego/hint/layout/x> "820.5"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "1746.4999389648438"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0002352> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/PR_000007766> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-5> <http://geneontology.org/lego/hint/layout/x> "560.75"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "1747.4999389648438"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0002352> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/PR_000007770> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-6> <http://geneontology.org/lego/hint/layout/x> "296"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "1723.4999389648438"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0002352> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/PR_000007771> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization> <http://geneontology.org/lego/hint/layout/x> "457.75"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "942.25"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.obolibrary.org/obo/RO_0019001> <http://www.co-ode.org/ontologies/ont.owl#seizures> ;
<http://purl.obolibrary.org/obo/RO_0002213> <http://www.co-ode.org/ontologies/ont.owl#seizures> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/GO_0051899> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://www.co-ode.org/ontologies/ont.owl#seizures> <http://geneontology.org/lego/hint/layout/x> "454.75"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://geneontology.org/lego/hint/layout/y> "821"^^<http://www.w3.org/2001/XMLSchema#string> ;
a <http://www.w3.org/2002/07/owl#NamedIndividual> , <http://purl.obolibrary.org/obo/NBO_0000025> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<https://noctua.apps.renci.org/model/AOP_10> <http://geneontology.org/lego/modelstate> "production"^^<http://www.w3.org/2001/XMLSchema#string> ;
a <http://www.w3.org/2002/07/owl#Ontology> ;
<http://purl.org/dc/elements/1.1/title> "Binding to the picrotoxin site of ionotropic GABA receptors leading to epileptic seizures in adult brain"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .

<http://geneontology.org/lego/hint/layout/x> a <http://www.w3.org/2002/07/owl#AnnotationProperty> .

Expand All @@ -120,73 +120,71 @@

<http://purl.obolibrary.org/obo/RO_0002352> a <http://www.w3.org/2002/07/owl#ObjectProperty> .

<http://purl.obolibrary.org/obo/RO_0019001> a <http://www.w3.org/2002/07/owl#ObjectProperty> .

<http://purl.org/dc/elements/1.1/title> a <http://www.w3.org/2002/07/owl#AnnotationProperty> .

<http://purl.org/dc/elements/1.1/contributor> a <http://www.w3.org/2002/07/owl#AnnotationProperty> .

<http://purl.org/dc/elements/1.1/date> a <http://www.w3.org/2002/07/owl#AnnotationProperty> .

_:t3934 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
_:t5232 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#chloride> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3935 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002212> ;
_:t5233 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002212> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-09-19"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3936 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
_:t5234 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#GABA-gated%20chloride%20ion%20channel%20activity> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-09-19"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3937 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
_:t5235 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#chemical%20synaptic%20transmission> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-09-19"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3938 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
_:t5236 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#excitatory%20postsynaptic%20potential> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-09-19"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3939 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
_:t5237 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-1> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3940 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
_:t5238 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-5> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3941 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
_:t5239 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002352> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#gamma-aminobutyric%20acid%20receptor%20subunit%20alpha-6> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#GABA%20receptor%20binding> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-10-18"^^<http://www.w3.org/2001/XMLSchema#string> .

_:t3942 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0019001> ;
_:t5240 <http://www.w3.org/2002/07/owl#annotatedProperty> <http://purl.obolibrary.org/obo/RO_0002213> ;
<http://www.w3.org/2002/07/owl#annotatedSource> <http://www.co-ode.org/ontologies/ont.owl#membrane%20depolarization> ;
<http://www.w3.org/2002/07/owl#annotatedTarget> <http://www.co-ode.org/ontologies/ont.owl#seizures> ;
a <http://www.w3.org/2002/07/owl#Axiom> ;
<http://purl.org/dc/elements/1.1/contributor> "https://orcid.org/0000-0001-9356-3475"^^<http://www.w3.org/2001/XMLSchema#string> ;
<http://purl.org/dc/elements/1.1/date> "2023-09-26"^^<http://www.w3.org/2001/XMLSchema#string> .
<http://purl.org/dc/elements/1.1/date> "2023-11-22"^^<http://www.w3.org/2001/XMLSchema#string> .
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