diff --git a/content/en/docs/zero-code/python/_index.md b/content/en/docs/zero-code/python/_index.md
index c9d4887282b1..5413707ca501 100644
--- a/content/en/docs/zero-code/python/_index.md
+++ b/content/en/docs/zero-code/python/_index.md
@@ -120,3 +120,35 @@ export GRPC_VERBOSITY=debug
 export GRPC_TRACE=http,call_error,connectivity_state
 opentelemetry-instrument python YOUR_APP.py
 ```
+
+### Bootstrap using uv
+
+When using the [uv](https://docs.astral.sh/uv/) package manager, you might face
+some difficulty when running `opentelemetry-bootstrap -a install`.
+
+Instead, you can generate the requirements dynamically and install them using
+`uv`.
+
+First, install the appropriate packages (or add them to your project file and
+run `uv sync`):
+
+```sh
+uv pip install opentelemetry-distro opentelemetry-exporter-otlp
+```
+
+Now, you can install the auto instrumentation:
+
+```sh
+uv run opentelemetry-bootstrap -a requirements | uv pip install --requirement -
+```
+
+Finally, use `uv run` to start your application (see
+[Configuring the agent](#configuring-the-agent)):
+
+```sh
+uv run opentelemetry-instrument python myapp.py
+```
+
+Please note that you have to reinstall the auto instrumentation every time you
+run `uv sync` or update existing packages. It is therefore recommended to make
+the installation part of your build pipeline.
diff --git a/static/refcache.json b/static/refcache.json
index 084a93c50e2e..8336adfe838d 100644
--- a/static/refcache.json
+++ b/static/refcache.json
@@ -2339,6 +2339,10 @@
     "StatusCode": 200,
     "LastSeen": "2024-08-30T17:38:37.903633988Z"
   },
+  "https://docs.astral.sh/uv/": {
+    "StatusCode": 200,
+    "LastSeen": "2024-11-21T10:24:48.633652602+01:00"
+  },
   "https://docs.aws.amazon.com/AWSSimpleQueueService/latest/SQSDeveloperGuide/sqs-message-metadata.html#sqs-message-system-attributes": {
     "StatusCode": 206,
     "LastSeen": "2024-01-18T08:53:50.0122-05:00"