NaN in synthetic likelihood #207
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Hi Dr.King, I have a quick question about synthetic likelihood. When I summarized the information of probes using |
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The synthetic likelihood is inversely proportional to the variance of the simulated probes. If the variance matrix has a zero eigenvalue, this will lead to an |
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Yes, I think the variance-covariance matrix is ill-conditioned. You may be able to resolve this issue by re-scaling the probes so that their variability is more of unit magnitude. Also, if some probes are redundant, i.e., they are almost perfectly well predicted by some combination of other probes, this can lead to ill-conditioning. |
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Yes, I think the variance-covariance matrix is ill-conditioned. You may be able to resolve this issue by re-scaling the probes so that their variability is more of unit magnitude. Also, if some probes are redundant, i.e., they are almost perfectly well predicted by some combination of other probes, this can lead to ill-conditioning.