We studied the functional impact of alternative splicing alterations in cancer, with special interest on their potential as tumor drivers. The article is available in Cell Reports.
- Switch statistics
- Immune cells/stroma contamination
- Functionality
- Tumorigenic evidences
- Events involved
- PSI study
- Whole-exome sequencing gene analysis
- Whole-genome sequencing gene analysis
- CNA analysis
- Mutual exclusion: comet
- Pfam domains
- Protein-protein interactions
- Protein-protein interactions stats
- Protein-protein interactions mutual exclusion
- Protein-protein interactions neighborhoods
- Neighborhood curation
The data was generated by applying the spada and scudo pipelines to transcript expression data generated by the TCGA project. The files necessary to replicate all these analyses are available here; it must be placed in a data/ folder inside the project.
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