diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index 51b024fc3..d4565e316 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -10396,13 +10396,14 @@ intersection_of: has_primary_input_or_output CHEBI:61360 ! globoside id: GO:0001576 name: globoside biosynthetic process namespace: biological_process -def: "The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)." [ISBN:0198506732] +def: "The chemical reactions and pathways resulting in the formation of a glycosphingolipid with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I)." [ISBN:0198506732] synonym: "globoside anabolism" EXACT [] synonym: "globoside biosynthesis" EXACT [] synonym: "globoside formation" EXACT [] synonym: "globoside synthesis" EXACT [] intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:61360 ! globoside +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29130" xsd:anyURI [Term] id: GO:0001577 @@ -172728,11 +172729,11 @@ synonym: "telomeric heterochromatin formation" RELATED [] synonym: "telomeric silencing" EXACT [GOC:bf] is_a: GO:0140719 ! constitutive heterochromatin formation relationship: occurs_in GO:0000781 ! chromosome, telomeric region -relationship: part_of GO:0032200 ! telomere organization property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19188" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/19308" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/22027" xsd:anyURI property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/23553" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29160" xsd:anyURI [Term] id: GO:0031510 @@ -195058,7 +195059,7 @@ is_a: GO:1990904 ! ribonucleoprotein complex [Term] id: GO:0033621 -name: nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts +name: nuclear mRNA surveillance of meiosis-specific transcripts namespace: biological_process def: "The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein." [PMID:16823445] comment: Note that it is speculated that higher eukaryotic YTH-family protein may be involved in similar mechanisms to suppress gene regulation during gametogenesis or general silencing. @@ -195067,8 +195068,10 @@ synonym: "mRNA breakdown, meiosis-specific transcripts" EXACT [] synonym: "mRNA catabolism, meiosis-specific transcripts" EXACT [] synonym: "mRNA degradation, meiosis-specific transcripts" EXACT [] synonym: "nuclear mRNA catabolic process, meiosis-specific transcripts" EXACT [] +synonym: "nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts" EXACT [] is_a: GO:0071028 ! nuclear mRNA surveillance property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26954" xsd:anyURI +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29246" xsd:anyURI [Term] id: GO:0033622 @@ -262647,8 +262650,9 @@ name: mitochondrial degradosome namespace: cellular_component def: "A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer." [PMID:10397341, PMID:9829834] synonym: "mtEXO" EXACT [PMID:10397341, PMID:9829834] -is_a: GO:0000177 ! cytoplasmic exosome (RNase complex) +is_a: GO:1905354 ! exoribonuclease complex relationship: part_of GO:0005739 ! mitochondrion +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29281" xsd:anyURI [Term] id: GO:0045026 @@ -265620,9 +265624,11 @@ id: GO:0045324 name: late endosome to vacuole transport namespace: biological_process def: "The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport." [PMID:11872141] +is_a: GO:0007034 ! vacuolar transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: has_target_end_location GO:0005773 ! vacuole intersection_of: has_target_start_location GO:0005770 ! late endosome +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29318" xsd:anyURI [Term] id: GO:0045325 @@ -448752,7 +448758,7 @@ name: regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein." [GOC:krc, PMID:24920274] intersection_of: GO:0065007 ! biological regulation -intersection_of: regulates GO:0033621 ! nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts +intersection_of: regulates GO:0033621 ! nuclear mRNA surveillance of meiosis-specific transcripts property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18757" xsd:anyURI created_by: krc creation_date: 2020-10-08T20:52:55Z @@ -448763,7 +448769,7 @@ name: negative regulation of nuclear-transcribed mRNA catabolic process, meiosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein." [GOC:krc, PMID:24920274] intersection_of: GO:0065007 ! biological regulation -intersection_of: negatively_regulates GO:0033621 ! nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts +intersection_of: negatively_regulates GO:0033621 ! nuclear mRNA surveillance of meiosis-specific transcripts property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18757" xsd:anyURI created_by: krc creation_date: 2020-10-08T21:01:06Z @@ -448774,7 +448780,7 @@ name: positive regulation of nuclear-transcribed mRNA catabolic process, meiosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein." [GOC:krc, PMID:24920274] intersection_of: GO:0065007 ! biological regulation -intersection_of: positively_regulates GO:0033621 ! nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts +intersection_of: positively_regulates GO:0033621 ! nuclear mRNA surveillance of meiosis-specific transcripts property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/18757" xsd:anyURI created_by: krc creation_date: 2020-10-08T21:09:03Z @@ -468069,6 +468075,27 @@ property_value: term_tracker_item "https://github.com/geneontology/go-ontology/i created_by: vw creation_date: 2024-10-11T13:09:12Z +[Term] +id: GO:0180049 +name: Mrh5C translation activator complex +namespace: cellular_component +def: "A protein complex capable of translation activator activity, and is involved in the activation of cox1 mRNA for translation. In fission yeast this complex consists of a scaffold (Sls1), a helicase (Mrh5), and PPR repeat proteins Prr4 and Mtf2." [PMID:38499152] +synonym: "Mrh5C complex" EXACT [] +is_a: GO:0032991 ! protein-containing complex +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29144" xsd:anyURI +created_by: vw +creation_date: 2024-12-02T13:17:12Z + +[Term] +id: GO:0180050 +name: protein-mitochondrial outer membrane tethering activity +namespace: molecular_function +def: "The binding activity of a molecule that brings together a protein or protein complex and a mitochondrial outer membrane lipid or membrane-associated protein, in order to maintain the localization of the protein, or protein complex at a specific mitochondrial outer membrane location." [GOC:vw] +is_a: GO:0043495 ! protein-membrane adaptor activity +property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29131" xsd:anyURI +created_by: vw +creation_date: 2024-12-02T13:24:07Z + [Term] id: GO:0198738 name: obsolete cell-cell signaling by wnt