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Problem with Rhea mapping 19669 , multiple false positives, large number of false postives #5492

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ValWood opened this issue Oct 27, 2024 · 4 comments

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@ValWood
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ValWood commented Oct 27, 2024

GO:1990606 membrane scission GTPase motor activity 8

guf1 |   | IEA with 19669 | GO_REF:0000116
ria1 |   | IEA with 19669 | GO_REF:0000116
sar1 |   | IEA with 19669 | GO_REF:0000116
tif213 |   | IEA with 19669 | GO_REF:0000116
tif52 |   | IEA with 19669 | GO_REF:0000116

These seem to be false positives
SPBC31F10.06c | sar1 | ADP-ribosylation factor Sar1
SPCC553.08c | ria1 | GTPase Ria1
SPAC1B3.04c | guf1 | mitochondrial elongation factor GTPase Guf1
SPBC17G9.09 | tif213 | translation initiation factor eIF2 gamma subunit
SPAC56F8.03 | tif52 | translation initiation factor eIF5B Tif52

@ValWood ValWood changed the title Problem with Rhea mapping 19669 , multiple false positives Problem with Rhea mapping 19669 , multiple false positives, large number of false postives Oct 27, 2024
@pgaudet
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pgaudet commented Oct 28, 2024

@ValWood

This is a broadMatch issue. We need the export to be fixed.... no point reporting these while the export is still not doing what we need it to.

I made this high priority.

@balhoff

@ValWood
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ValWood commented Oct 28, 2024

Yep that would be good to fix with high priority . It's causing a lot of misannotations.

I had to filter over 400 incorrect IEAs for Pombe just from these few tickets! (Although these were the only problems I spotted, most of the rest are OK—or at least don't create tens of annotations.
I checked every mapping with >4 propagated annotation.

@balhoff
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balhoff commented Oct 28, 2024

Filtering broad matches is done now and should appear in snapshot soon.

@ValWood
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ValWood commented Oct 28, 2024

Awsome, thanks!

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