diff --git a/packages/react-native/src/private/webapis/dom/events/EventHandlerAttributes.js b/packages/react-native/src/private/webapis/dom/events/EventHandlerAttributes.js
new file mode 100644
index 00000000000000..5b9480383f2432
--- /dev/null
+++ b/packages/react-native/src/private/webapis/dom/events/EventHandlerAttributes.js
@@ -0,0 +1,130 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ * @flow strict
+ * @format
+ */
+
+/**
+ * This module provides helpers for classes to implement event handler IDL
+ * attributes, as defined in https://html.spec.whatwg.org/multipage/webappapis.html#event-handler-idl-attributes.
+ *
+ * Expected usage:
+ * ```
+ * import {getEventHandlerAttribute, setEventHandlerAttribute} from '../path/to/EventHandlerAttributes';
+ *
+ * class EventTargetSubclass extends EventTarget {
+ *   get oncustomevent(): EventListener | null {
+ *     return getEventHandlerAttribute(this, 'customEvent');
+ *   }
+ *
+ *   set oncustomevent(listener: EventListener | null) {
+ *     setEventHandlerAttribute(this, 'customEvent', listener);
+ *   }
+ * }
+ *
+ * const eventTargetInstance = new EventTargetSubclass();
+ *
+ * eventTargetInstance.oncustomevent = (event: Event) => {
+ *   console.log('custom event received');
+ * };
+ * eventTargetInstance.dispatchEvent(new Event('customEvent'));
+ * // Logs 'custom event received' to the console.
+ *
+ * eventTargetInstance.oncustomevent = null;
+ * eventTargetInstance.dispatchEvent(new Event('customEvent'));
+ * // Does not log anything to the console.
+ * ```
+ */
+
+import type EventTarget from './EventTarget';
+import type {EventCallback} from './EventTarget';
+
+type EventHandler = $ReadOnly<{
+  handleEvent: EventCallback,
+}>;
+type EventHandlerAttributeMap = Map<string, EventHandler | null>;
+
+const EVENT_HANDLER_CONTENT_ATTRIBUTE_MAP_KEY = Symbol(
+  'eventHandlerAttributeMap',
+);
+
+function getEventHandlerAttributeMap(
+  target: EventTarget,
+): ?EventHandlerAttributeMap {
+  // $FlowExpectedError[prop-missing]
+  return target[EVENT_HANDLER_CONTENT_ATTRIBUTE_MAP_KEY];
+}
+
+function setEventHandlerAttributeMap(
+  target: EventTarget,
+  map: ?EventHandlerAttributeMap,
+) {
+  // $FlowExpectedError[prop-missing]
+  target[EVENT_HANDLER_CONTENT_ATTRIBUTE_MAP_KEY] = map;
+}
+
+/**
+ * Returns the event listener registered as an event handler IDL attribute for
+ * the given target and type.
+ *
+ * Should be used to get the current value for `target.on{type}`.
+ */
+export function getEventHandlerAttribute(
+  target: EventTarget,
+  type: string,
+): EventCallback | null {
+  const listener = getEventHandlerAttributeMap(target)?.get(type);
+  return listener != null ? listener.handleEvent : null;
+}
+
+/**
+ * Sets the event listener registered as an event handler IDL attribute for
+ * the given target and type.
+ *
+ * Should be used to set a value for `target.on{type}`.
+ */
+export function setEventHandlerAttribute(
+  target: EventTarget,
+  type: string,
+  callback: EventCallback | null,
+): void {
+  let map = getEventHandlerAttributeMap(target);
+  if (map != null) {
+    const currentListener = map.get(type);
+    if (currentListener) {
+      target.removeEventListener(type, currentListener);
+      map.delete(type);
+    }
+  }
+
+  if (
+    callback != null &&
+    (typeof callback === 'function' || typeof callback === 'object')
+  ) {
+    // Register the listener as a different object in the target so it
+    // occupies its own slot and cannot be removed via `removeEventListener`.
+    const listener = {
+      handleEvent: callback,
+    };
+
+    try {
+      target.addEventListener(type, listener);
+      // If adding the listener fails, we don't store the value
+      if (map == null) {
+        map = new Map();
+        setEventHandlerAttributeMap(target, map);
+      }
+      map.set(type, listener);
+    } catch (e) {
+      // Assigning incorrect listener does not throw in setters.
+    }
+  }
+
+  if (map != null && map.size === 0) {
+    setEventHandlerAttributeMap(target, null);
+  }
+}
diff --git a/packages/react-native/src/private/webapis/dom/events/EventTarget.js b/packages/react-native/src/private/webapis/dom/events/EventTarget.js
index 1753e5ac5de207..9697800ac35c0a 100644
--- a/packages/react-native/src/private/webapis/dom/events/EventTarget.js
+++ b/packages/react-native/src/private/webapis/dom/events/EventTarget.js
@@ -33,11 +33,11 @@ import {
   INTERNAL_DISPATCH_METHOD_KEY,
 } from './internals/EventTargetInternals';
 
-export type EventListener =
-  | ((event: Event) => void)
-  | interface {
-      handleEvent(event: Event): void,
-    };
+export type EventCallback = (event: Event) => void;
+export type EventHandler = interface {
+  handleEvent(event: Event): void,
+};
+export type EventListener = EventCallback | EventHandler;
 
 export type EventListenerOptions = {
   capture?: boolean,
diff --git a/packages/react-native/src/private/webapis/dom/events/__tests__/EventHandlerAttributes-itest.js b/packages/react-native/src/private/webapis/dom/events/__tests__/EventHandlerAttributes-itest.js
new file mode 100644
index 00000000000000..d5f5c6e507dd09
--- /dev/null
+++ b/packages/react-native/src/private/webapis/dom/events/__tests__/EventHandlerAttributes-itest.js
@@ -0,0 +1,205 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ * @flow strict-local
+ * @format
+ * @oncall react_native
+ * @fantom_flags enableAccessToHostTreeInFabric:true
+ */
+
+// flowlint unsafe-getters-setters:off
+
+import '../../../../../../Libraries/Core/InitializeCore.js';
+
+import type {EventListener} from '../EventTarget';
+
+import Event from '../Event';
+import {
+  getEventHandlerAttribute,
+  setEventHandlerAttribute,
+} from '../EventHandlerAttributes';
+import EventTarget from '../EventTarget';
+
+class EventTargetSubclass extends EventTarget {
+  get oncustomevent(): EventListener | null {
+    return getEventHandlerAttribute(this, 'customEvent');
+  }
+
+  set oncustomevent(listener: EventListener | null) {
+    setEventHandlerAttribute(this, 'customEvent', listener);
+  }
+}
+
+describe('EventHandlerAttributes', () => {
+  it('should register event listeners assigned to the attributes', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = jest.fn();
+    target.oncustomevent = listener;
+
+    expect(target.oncustomevent).toBe(listener);
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+    expect(listener.mock.lastCall[0]).toBe(event);
+  });
+
+  it('should NOT register values assigned to the attributes if they are not an event listener', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = Symbol();
+    // $FlowExpectedError[incompatible-type]
+    target.oncustomevent = listener;
+
+    expect(target.oncustomevent).toBe(null);
+
+    const event = new Event('customEvent');
+
+    // This doesn't fail.
+    target.dispatchEvent(event);
+  });
+
+  it('should remove event listeners assigned to the attributes when reassigning them to null', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = jest.fn();
+    target.oncustomevent = listener;
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+    expect(listener.mock.lastCall[0]).toBe(event);
+
+    target.oncustomevent = null;
+
+    expect(target.oncustomevent).toBe(null);
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+  });
+
+  it('should remove event listeners assigned to the attributes when reassigning them to a different listener', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = jest.fn();
+    target.oncustomevent = listener;
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+    expect(listener.mock.lastCall[0]).toBe(event);
+
+    const newListener = jest.fn();
+    target.oncustomevent = newListener;
+
+    expect(target.oncustomevent).toBe(newListener);
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+    expect(newListener).toHaveBeenCalledTimes(1);
+    expect(newListener.mock.lastCall[0]).toBe(event);
+  });
+
+  it('should remove event listeners assigned to the attributes when reassigning them to an incorrect listener value', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = jest.fn();
+    target.oncustomevent = listener;
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+    expect(listener.mock.lastCall[0]).toBe(event);
+
+    const newListener = Symbol();
+    // $FlowExpectedError[incompatible-type]
+    target.oncustomevent = newListener;
+
+    expect(target.oncustomevent).toBe(null);
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(1);
+  });
+
+  it('should interoperate with listeners registered via `addEventListener`', () => {
+    const target = new EventTargetSubclass();
+
+    let order = 0;
+
+    const regularListener1: JestMockFn<[Event], void> = jest.fn(() => {
+      // $FlowExpectedError[prop-missing]
+      regularListener1.order = order++;
+    });
+    target.addEventListener('customEvent', regularListener1);
+
+    const attributeListener: JestMockFn<[Event], void> = jest.fn(() => {
+      // $FlowExpectedError[prop-missing]
+      attributeListener.order = order++;
+    });
+    target.oncustomevent = attributeListener;
+
+    const regularListener2: JestMockFn<[Event], void> = jest.fn(() => {
+      // $FlowExpectedError[prop-missing]
+      regularListener2.order = order++;
+    });
+    target.addEventListener('customEvent', regularListener2);
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(regularListener1).toHaveBeenCalledTimes(1);
+    expect(regularListener1.mock.lastCall[0]).toBe(event);
+    // $FlowExpectedError[prop-missing]
+    expect(regularListener1.order).toBe(0);
+
+    expect(attributeListener).toHaveBeenCalledTimes(1);
+    expect(attributeListener.mock.lastCall[0]).toBe(event);
+    // $FlowExpectedError[prop-missing]
+    expect(attributeListener.order).toBe(1);
+
+    expect(regularListener2).toHaveBeenCalledTimes(1);
+    expect(regularListener2.mock.lastCall[0]).toBe(event);
+    // $FlowExpectedError[prop-missing]
+    expect(regularListener2.order).toBe(2);
+  });
+
+  it('should not be considered the same callback when adding it again via `addEventListener`', () => {
+    const target = new EventTargetSubclass();
+
+    const listener = jest.fn();
+
+    target.addEventListener('customEvent', listener);
+    target.oncustomevent = listener;
+
+    const event = new Event('customEvent');
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(2);
+    expect(listener.mock.calls[0][0]).toBe(event);
+    expect(listener.mock.calls[1][0]).toBe(event);
+
+    target.removeEventListener('customEvent', listener);
+
+    target.dispatchEvent(event);
+
+    expect(listener).toHaveBeenCalledTimes(3);
+    expect(listener.mock.lastCall[0]).toBe(event);
+  });
+});