diff --git a/cmd/podman/root.go b/cmd/podman/root.go
index 60d554f40a0..f1be3932293 100644
--- a/cmd/podman/root.go
+++ b/cmd/podman/root.go
@@ -582,12 +582,6 @@ func rootFlags(cmd *cobra.Command, podmanConfig *entities.PodmanConfig) {
 		pFlags.StringVar(&podmanConfig.ConmonPath, conmonFlagName, "", "Path of the conmon binary")
 		_ = cmd.RegisterFlagCompletionFunc(conmonFlagName, completion.AutocompleteDefault)
 
-		// TODO (6.0): --network-cmd-path is deprecated, remove this option with the next major release
-		// We need to find all the places that use r.config.Engine.NetworkCmdPath and remove it
-		networkCmdPathFlagName := "network-cmd-path"
-		pFlags.StringVar(&podmanConfig.ContainersConf.Engine.NetworkCmdPath, networkCmdPathFlagName, podmanConfig.ContainersConfDefaultsRO.Engine.NetworkCmdPath, "Path to the command for configuring the network")
-		_ = cmd.RegisterFlagCompletionFunc(networkCmdPathFlagName, completion.AutocompleteDefault)
-
 		networkConfigDirFlagName := "network-config-dir"
 		pFlags.StringVar(&podmanConfig.ContainersConf.Network.NetworkConfigDir, networkConfigDirFlagName, podmanConfig.ContainersConfDefaultsRO.Network.NetworkConfigDir, "Path of the configuration directory for networks")
 		_ = cmd.RegisterFlagCompletionFunc(networkConfigDirFlagName, completion.AutocompleteDefault)
diff --git a/docs/source/locale/ja/LC_MESSAGES/markdown.po b/docs/source/locale/ja/LC_MESSAGES/markdown.po
index 810190da4a6..9c426460817 100644
--- a/docs/source/locale/ja/LC_MESSAGES/markdown.po
+++ b/docs/source/locale/ja/LC_MESSAGES/markdown.po
@@ -31333,10 +31333,6 @@ msgid ""
 "Windows (excluding WSL2) machines"
 msgstr ""
 
-#: ../../source/markdown/podman.1.md:98
-msgid "**--network-cmd-path**=*path*"
-msgstr ""
-
 #: ../../source/markdown/podman.1.md:99
 msgid ""
 "Path to the `slirp4netns(1)` command binary to use for setting up a "
diff --git a/docs/source/markdown/podman.1.md b/docs/source/markdown/podman.1.md
index d3869aee5b7..7b837fe4bb9 100644
--- a/docs/source/markdown/podman.1.md
+++ b/docs/source/markdown/podman.1.md
@@ -104,11 +104,6 @@ Load the specified `containers.conf(5)` module.  Can be an absolute or relative
 This flag is not supported on the remote client, including Mac and Windows (excluding WSL2) machines.
 Further note that the flag is a root-level flag and must be specified before any Podman sub-command.
 
-#### **--network-cmd-path**=*path*
-Path to the `slirp4netns(1)` command binary to use for setting up a slirp4netns network.
-If "" is used, then the binary will first be searched using the `helper_binaries_dir` option in `containers.conf`, and second using the `$PATH` environment variable.
-**Note:** This option is deprecated and will be removed with Podman 6.0. Use the `helper_binaries_dir` option in `containers.conf` instead.
-
 #### **--network-config-dir**=*directory*
 
 Path to the directory where network configuration files are located.
diff --git a/libpod/info_linux.go b/libpod/info_linux.go
index 108d5cf4576..a056c022f6c 100644
--- a/libpod/info_linux.go
+++ b/libpod/info_linux.go
@@ -50,10 +50,7 @@ func (r *Runtime) setPlatformHostInfo(info *define.HostInfo) error {
 
 	info.CgroupsVersion = "v2"
 
-	slirp4netnsPath := r.config.Engine.NetworkCmdPath
-	if slirp4netnsPath == "" {
-		slirp4netnsPath, _ = r.config.FindHelperBinary(slirp4netns.BinaryName, true)
-	}
+	slirp4netnsPath, _ := r.config.FindHelperBinary(slirp4netns.BinaryName, true)
 	if slirp4netnsPath != "" {
 		ver, err := version.Program(slirp4netnsPath)
 		if err != nil {
diff --git a/libpod/options.go b/libpod/options.go
index 41d6bc4a78c..5e10a63f04a 100644
--- a/libpod/options.go
+++ b/libpod/options.go
@@ -180,20 +180,6 @@ func WithConmonPath(path string) RuntimeOption {
 	}
 }
 
-// WithNetworkCmdPath specifies the path to the slirp4netns binary which manages the
-// runtime.
-func WithNetworkCmdPath(path string) RuntimeOption {
-	return func(rt *Runtime) error {
-		if rt.valid {
-			return define.ErrRuntimeFinalized
-		}
-
-		rt.config.Engine.NetworkCmdPath = path
-
-		return nil
-	}
-}
-
 // WithNetworkBackend specifies the name of the network backend.
 func WithNetworkBackend(name string) RuntimeOption {
 	return func(rt *Runtime) error {
diff --git a/pkg/domain/infra/runtime_libpod.go b/pkg/domain/infra/runtime_libpod.go
index 3c2d02bbb04..64f8992487a 100644
--- a/pkg/domain/infra/runtime_libpod.go
+++ b/pkg/domain/infra/runtime_libpod.go
@@ -164,9 +164,6 @@ func getRuntime(ctx context.Context, fs *flag.FlagSet, opts *engineOpts) (*libpo
 	if fs.Changed("tmpdir") {
 		options = append(options, libpod.WithTmpDir(cfg.ContainersConf.Engine.TmpDir))
 	}
-	if fs.Changed("network-cmd-path") {
-		options = append(options, libpod.WithNetworkCmdPath(cfg.ContainersConf.Engine.NetworkCmdPath))
-	}
 	if fs.Changed("network-backend") {
 		options = append(options, libpod.WithNetworkBackend(cfg.ContainersConf.Network.NetworkBackend))
 	}
diff --git a/test/e2e/quadlet/globalargs.network b/test/e2e/quadlet/globalargs.network
index ebb74c79154..553250d1440 100644
--- a/test/e2e/quadlet/globalargs.network
+++ b/test/e2e/quadlet/globalargs.network
@@ -1,7 +1,5 @@
-## assert-podman-global-args "network" "--network-cmd-path=/usr/bin/network-cmd"
 ## assert-podman-global-args "network" "--network-config-dir=/etc/network-config"
 ## assert-podman-global-args "network" "--log-level=debug"
 
 [Network]
-GlobalArgs=--network-cmd-path=/usr/bin/network-cmd
 GlobalArgs=--network-config-dir=/etc/network-config --log-level=debug