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Long time I am struggling how to provide GISTIC required input like Num_Probes and Segment_Mean
I have called somatic copy number by scatngs and I have copy number output file (attached); In scatngs reference paper says in this file we have
Segment number
Chromosome
Start position (origin-1)
End position (origin-1)
Major copy number—normal
Minor copy number—normal
Major copy number—tumor
Minor copy number—tumor
I am wondering how I can get
Num_Probes and Segment_MeanFrom this file?
People say
Segment_Mean = log2(tumour copy number / 2)
So, does that mean I should add up Major copy number—tumor and Minor copy number—tumor to get tumour copy number? for getting Num_Probes what should I do?
Any help please?
Thanks a lot in advance
The text was updated successfully, but these errors were encountered:
Please do not open GitHub issues for these sort of questions. You're already asking bioinformatics SE for help, do not open GitHub issues for issues that are not related to the tool's functionality.
That does not mean GitHub is the place to discuss this problem you're facing, especially given it's a problem you're having trying to extract something for a downstream step. Think about it this way - you should be using a GitHub issue to produce a bug report for a problem that you could solve by changing the tool's source code. Is this such a problem?
Sorry
Long time I am struggling how to provide GISTIC required input like
Num_Probes
andSegment_Mean
I have called somatic copy number by
scatngs
and I have copy number output file (attached); In scatngs reference paper says in this file we haveMinor copy number—tumor
I am wondering how I can get
Num_Probes
andSegment_Mean
From this file?People say
Segment_Mean = log2(tumour copy number / 2)
So, does that mean I should add up
Major copy number—tumor
andMinor copy number—tumor
to get tumour copy number? for getting Num_Probes what should I do?Any help please?
Thanks a lot in advance
The text was updated successfully, but these errors were encountered: