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Merge pull request #1556 from biolink/release-candidate-v4.2.6-rc5
Release candidate v4.2.6 rc5
2 parents f9e2e66 + f793347 commit 4b910e4

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biolink-model.yaml

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# Version should be kept in sync with primary Git repository release tag
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version: 4.2.5
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version: 4.2.6-rc5
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## ------------
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##

class_prefixes.yaml

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# Version should be kept in sync with primary Git repository release tag
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version: 4.2.5
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version: 4.2.6-rc5
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default_prefix: biolink
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default_range: string

poetry.lock

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project/graphql/biolink_model.graphql

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# metamodel_version: 1.7.0
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# version: 4.2.5
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# version: 4.2.6-rc5
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enum AgentTypeEnum
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{
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manual_agent
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automated_agent
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data_analysis_pipeline
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computational_model
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text_mining_agent
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image_processing_agent
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manual_validation_of_automated_agent
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not_provided
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}
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enum ApprovalStatusEnum
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{
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discovery_and_development_phase
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preclinical_research_phase
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fda_clinical_research_phase
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fda_review_phase_4
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fda_post_market_safety_review
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fda_clinical_research_phase_1
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fda_clinical_research_phase_2
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fda_clinical_research_phase_3
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fda_clinical_research_phase_4
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fda_fast_track
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fda_breakthrough_therapy
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fda_accelerated_approval
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fda_priority_review
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regular_fda_approval
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post_approval_withdrawal
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}
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enum CausalMechanismQualifierEnum
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{
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binding
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inhibition
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antibody_inhibition
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antagonism
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molecular_channel_blockage
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inverse_agonism
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negative_allosteric_modulation
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agonism
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molecular_channel_opening
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positive_allosteric_modulation
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potentiation
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activation
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inducer
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transcriptional_regulation
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signaling_mediated_control
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stabilization
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stimulation
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releasing_activity
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}
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enum ChemicalEntityDerivativeEnum
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{
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metabolite
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}
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enum ChemicalOrGeneOrGeneProductFormOrVariantEnum
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{
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genetic_variant_form
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modified_form
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loss_of_function_variant_form
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gain_of_function_variant_form
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polymorphic_form
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snp_form
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analog_form
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}
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enum ClinicalApprovalStatusEnum
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{
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approved_for_condition
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fda_approved_for_condition
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not_approved_for_condition
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post_approval_withdrawal
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off_label_use
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not_provided
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}
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enum DirectionQualifierEnum
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{
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increased
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upregulated
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decreased
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downregulated
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}
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enum DrugAvailabilityEnum
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{
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over_the_counter
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prescription
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}
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enum DrugDeliveryEnum
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{
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inhalation
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oral
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absorption_through_the_skin
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intravenous_injection
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}
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enum DruggableGeneCategoryEnum
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{
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tclin
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tbio
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tchem
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tdark
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}
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enum FDAIDAAdverseEventEnum
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{
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life_threatening_adverse_event
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serious_adverse_event
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suspected_adverse_reaction
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unexpected_adverse_event
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}
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enum GeneOrGeneProductOrChemicalEntityAspectEnum
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{
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activity_or_abundance
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abundance
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activity
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expression
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synthesis
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degradation
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cleavage
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hydrolysis
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metabolic_processing
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mutation_rate
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stability
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folding
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localization
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transport
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absorption
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aggregation
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interaction
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release
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secretion
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uptake
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splicing
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molecular_interaction
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guanyl_nucleotide_exchange
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adenyl_nucleotide_exchange
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molecular_modification
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acetylation
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acylation
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alkylation
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amination
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carbamoylation
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ethylation
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glutathionylation
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glycation
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glycosylation
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glucuronidation
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n_linked_glycosylation
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o_linked_glycosylation
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hydroxylation
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lipidation
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farnesylation
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geranoylation
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myristoylation
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palmitoylation
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prenylation
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methylation
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nitrosation
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nucleotidylation
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phosphorylation
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ribosylation
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ADP__HYPHEN_MINUS__ribosylation
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sulfation
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sumoylation
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ubiquitination
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oxidation
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reduction
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carboxylation
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}
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enum GeneOrGeneProductOrChemicalPartQualifierEnum
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{
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__3_prime_utr
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__5_prime_utr
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polya_tail
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promoter
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enhancer
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exon
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intron
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}
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enum KnowledgeLevelEnum
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{
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knowledge_assertion
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logical_entailment
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prediction
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statistical_association
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observation
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not_provided
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}
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enum LogicalInterpretationEnum
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{
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some_some
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all_some
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inverse_all_some
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}
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enum PhaseEnum
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{
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__0
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__1
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__2
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}
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enum ReactionDirectionEnum
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{
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left_to_right
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right_to_left
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bidirectional
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neutral
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}
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enum ReactionSideEnum
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{
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left
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right
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}
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enum ResearchPhaseEnum
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{
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pre_clinical_research_phase
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clinical_trial_phase
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clinical_trial_phase_1
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clinical_trial_phase_2
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clinical_trial_phase_3
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clinical_trial_phase_4
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not_provided
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}
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enum ResourceRoleEnum
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{
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primary_knowledge_source
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aggregator_knowledge_source
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supporting_data_source
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}
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enum SequenceEnum
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{
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na
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aa
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}
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enum StrandEnum
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{
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__PLUS_SIGN__
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__HYPHEN_MINUS__
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__FULL_STOP__
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__QUESTION_MARK__
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}
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type AccessibleDnaRegion implements GenomicEntity, ChemicalEntityOrGeneOrGeneProduct, PhysicalEssence, OntologyClass
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{
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id: String!

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