diff --git a/.github/workflows/cpp_extra.yml b/.github/workflows/cpp_extra.yml
index b38ccaa2779..50ea4ebe61a 100644
--- a/.github/workflows/cpp_extra.yml
+++ b/.github/workflows/cpp_extra.yml
@@ -395,6 +395,9 @@ jobs:
           export ARROW_CMAKE_ARGS="-DODBC_INCLUDE_DIR=$ODBC_INCLUDE_DIR"
           export CXXFLAGS="$CXXFLAGS -I$ODBC_INCLUDE_DIR"
           ci/scripts/cpp_build.sh $(pwd) $(pwd)/build
+      - name: Register Flight SQL ODBC Driver
+        run: |
+          sudo cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc.sh $(pwd)/build/cpp/debug/libarrow_flight_sql_odbc.dylib
       - name: Test
         shell: bash
         run: |
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 566ade91721..a33aa3acb47 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -353,6 +353,7 @@ repos:
           ?^cpp/build-support/update-thrift\.sh$|
           ?^cpp/examples/minimal_build/run\.sh$|
           ?^cpp/examples/tutorial_examples/run\.sh$|
+          ?^cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc\.sh$|
           ?^dev/release/05-binary-upload\.sh$|
           ?^dev/release/08-binary-verify\.sh$|
           ?^dev/release/binary-recover\.sh$|
@@ -379,6 +380,7 @@ repos:
         files: >-
           (
           ?^ci/scripts/python_test_type_annotations\.sh$|
+          ?^cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc\.sh$|
           ?^dev/release/05-binary-upload\.sh$|
           ?^dev/release/binary-recover\.sh$|
           ?^dev/release/post-03-binary\.sh$|
diff --git a/cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc.sh b/cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc.sh
new file mode 100755
index 00000000000..069c534c297
--- /dev/null
+++ b/cpp/src/arrow/flight/sql/odbc/install/mac/install_odbc.sh
@@ -0,0 +1,77 @@
+#!/bin/bash
+#
+# Licensed to the Apache Software Foundation (ASF) under one
+# or more contributor license agreements.  See the NOTICE file
+# distributed with this work for additional information
+# regarding copyright ownership.  The ASF licenses this file
+# to you under the Apache License, Version 2.0 (the
+# "License"); you may not use this file except in compliance
+# with the License.  You may obtain a copy of the License at
+#
+#   http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing,
+# software distributed under the License is distributed on an
+# "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
+# KIND, either express or implied.  See the License for the
+# specific language governing permissions and limitations
+# under the License.
+
+# Used by macOS ODBC installer script `install_odbc_ini.sh` and macOS ODBC testing
+
+set -euo pipefail
+
+# Admin privilege is needed to add ODBC driver registration
+if [ $EUID -ne 0 ]; then
+  echo "Please run this script with sudo"
+  exit 1
+fi
+
+ODBC_64BIT="$1"
+
+if [[ -z "$ODBC_64BIT" ]]; then
+  echo "error: 64-bit driver is not specified. Call format: install_odbc abs_path_to_64_bit_driver"
+  exit 1
+fi
+
+if [ ! -f "$ODBC_64BIT" ]; then
+  echo "64-bit driver can not be found: $ODBC_64BIT"
+  echo "Call format: install_odbc abs_path_to_64_bit_driver"
+  exit 1
+fi
+
+USER_ODBCINST_FILE="$HOME/Library/ODBC/odbcinst.ini"
+DRIVER_NAME="Apache Arrow Flight SQL ODBC Driver"
+
+mkdir -p "$HOME"/Library/ODBC
+
+touch "$USER_ODBCINST_FILE"
+
+if grep -q "^\[$DRIVER_NAME\]" "$USER_ODBCINST_FILE"; then
+  echo "Driver [$DRIVER_NAME] already exists in odbcinst.ini"
+else
+  echo "Adding [$DRIVER_NAME] to odbcinst.ini..."
+  echo "
+[$DRIVER_NAME]
+Description=An ODBC Driver for Apache Arrow Flight SQL
+Driver=$ODBC_64BIT
+" >>"$USER_ODBCINST_FILE"
+fi
+
+# Check if [ODBC Drivers] section exists
+if grep -q '^\[ODBC Drivers\]' "$USER_ODBCINST_FILE"; then
+  # Section exists: check if driver entry exists
+  if ! grep -q "^${DRIVER_NAME}=" "$USER_ODBCINST_FILE"; then
+    # Driver entry does not exist, add under [ODBC Drivers]
+    sed -i '' "/^\[ODBC Drivers\]/a\\
+${DRIVER_NAME}=Installed
+" "$USER_ODBCINST_FILE"
+  fi
+else
+  # Section doesn't exist, append both section and driver entry at end
+  {
+    echo ""
+    echo "[ODBC Drivers]"
+    echo "${DRIVER_NAME}=Installed"
+  } >>"$USER_ODBCINST_FILE"
+fi