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DESCRIPTION
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DESCRIPTION
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Package: LinRace
Type: Package
Title: cell division history reconstruction of single cells using paired lineage barcode and gene expression data
Version: 0.1.0
Author: Xinhai Pan
Maintainer: The package maintainer <[email protected]>
Description: LinRace (Lineage Reconstruction with asymmetric cell division model), integrates lineage barcode and gene expression data using asymmetric cell division model and infers cell lineages and ancestral cell states using Neighbor-Joining and maximum-likelihood heuristics. On both simulated and real data, LinRace outputs more accurate cell division trees than existing methods. With inferred ancestral states, LinRace can also show how a progenitor cell generates a large population of cells with various functionalities.
License: MIT license
Encoding: UTF-8
LazyData: true
Suggests:
knitr,
rmarkdown
VignetteBuilder: knitr
RoxygenNote: 7.2.3
Imports:
dplyr,
DCLEAR,
data.table,
phangorn,
ape,
dyno,
slingshot,
TreeTools,
castor,
destiny,
magrittr,
Depends:
R(>= 3.5.0)