diff --git a/Project.toml b/Project.toml
index 3219992c..6322bfa7 100644
--- a/Project.toml
+++ b/Project.toml
@@ -44,7 +44,7 @@ ChainRulesCore = "1.16"
 DiffResults = "1"
 Distributions = "0.25.111"
 DocStringExtensions = "0.8, 0.9"
-Enzyme = "0.12.32"
+Enzyme = "0.13"
 FillArrays = "1.3"
 ForwardDiff = "0.10.36"
 Functors = "0.4"
diff --git a/ext/AdvancedVIEnzymeExt.jl b/ext/AdvancedVIEnzymeExt.jl
index 45b3c547..3b68d531 100644
--- a/ext/AdvancedVIEnzymeExt.jl
+++ b/ext/AdvancedVIEnzymeExt.jl
@@ -18,11 +18,13 @@ end
 function AdvancedVI.value_and_gradient!(
     ::ADTypes.AutoEnzyme, f, x::AbstractVector{<:Real}, out::DiffResults.MutableDiffResult
 )
-    Enzyme.API.runtimeActivity!(true)
     ∇x = DiffResults.gradient(out)
     fill!(∇x, zero(eltype(∇x)))
     _, y = Enzyme.autodiff(
-        Enzyme.ReverseWithPrimal, Enzyme.Const(f), Enzyme.Active, Enzyme.Duplicated(x, ∇x)
+        Enzyme.set_runtime_activity(Enzyme.ReverseWithPrimal, true),
+        Enzyme.Const(f),
+        Enzyme.Active,
+        Enzyme.Duplicated(x, ∇x),
     )
     DiffResults.value!(out, y)
     return out
@@ -35,11 +37,10 @@ function AdvancedVI.value_and_gradient!(
     aux,
     out::DiffResults.MutableDiffResult,
 )
-    Enzyme.API.runtimeActivity!(true)
     ∇x = DiffResults.gradient(out)
     fill!(∇x, zero(eltype(∇x)))
     _, y = Enzyme.autodiff(
-        Enzyme.ReverseWithPrimal,
+        Enzyme.set_runtime_activity(Enzyme.ReverseWithPrimal, true),
         Enzyme.Const(f),
         Enzyme.Active,
         Enzyme.Duplicated(x, ∇x),
diff --git a/test/Project.toml b/test/Project.toml
index 018198d1..ca0fc384 100644
--- a/test/Project.toml
+++ b/test/Project.toml
@@ -29,7 +29,6 @@ Bijectors = "0.13"
 DiffResults = "1.0"
 Distributions = "0.25.111"
 DistributionsAD = "0.6.45"
-Enzyme = "0.12.32"
 FillArrays = "1.6.1"
 ForwardDiff = "0.10.36"
 Functors = "0.4.5"