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What is CCF_std/CCF_CI_High value, how can I get it? #164

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LiuXiaodong1 opened this issue Aug 13, 2020 · 3 comments
Open

What is CCF_std/CCF_CI_High value, how can I get it? #164

LiuXiaodong1 opened this issue Aug 13, 2020 · 3 comments
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@LiuXiaodong1
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This package needs that value to identify clonal/subclonal mutations. I can calculate CCF use EstimateClonality, but what's the difference between CCF and CCF_std?

@qindan2008
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I have the same problem. I get CCF with TitanCNA which output CellularPrevalence but no CellularPrevalence_std. How can I get it?

Thank you.

@cocoMA2020
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I have the same question.

@Niinleslie
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@qindan2008 @cocoMA2020
The CCF_std represents the mean standard deviation of the predicted CCF for each mutation. The definition of the clonal status of mutations will be more accurate to integrate estimated CCF and CCF_std. If CCF_std is not available, you can set it as 0 for simplicity.

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