diff --git a/src/AnalysisPage/GraphicalClustering/Pass1bLandscapeTissues/ADRNL.jsx b/src/AnalysisPage/GraphicalClustering/Pass1bLandscapeTissues/ADRNL.jsx index f58acabd..d93eb3b8 100644 --- a/src/AnalysisPage/GraphicalClustering/Pass1bLandscapeTissues/ADRNL.jsx +++ b/src/AnalysisPage/GraphicalClustering/Pass1bLandscapeTissues/ADRNL.jsx @@ -4,6 +4,7 @@ import { tocbotConfig, pass1b06GraphicalClusteringLandscapeImageLocation, } from '../sharedLib'; +import DataVizLink from '../components/dataVizLink'; function GraphicalAnalysisAdrenal() { // initialize table of contents @@ -36,6 +37,11 @@ function GraphicalAnalysisAdrenal() {
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+ + {`Explore interactive ${title} visualization`} + +
+ ); +} + +DataVizLink.propTypes = { + title: PropTypes.string.isRequired, + tissue: PropTypes.string.isRequired, + plotType: PropTypes.string.isRequired, +}; + +export default DataVizLink; diff --git a/src/AnnouncementsPage/announcements.json b/src/AnnouncementsPage/announcements.json index be7bf866..9b5e9ebd 100644 --- a/src/AnnouncementsPage/announcements.json +++ b/src/AnnouncementsPage/announcements.json @@ -132,5 +132,95 @@ "gaEventAction": "MotrpacRatTraining6moData R package" } ] + }, + { + "aid": 7, + "posted_date": "2024-05-01", + "title": "MoTrPAC animal molecular adaptations study published in Cell Genomics", + "content": "In an integrated analysis of DNA methylation, chromatin accessibility, and transcriptome in eight tissues from the control group, we identified distinct molecular landscapes across rat tissues. We demonstrated that the transcriptional and epigenetic responses to eight weeks of exercise training are predominantly tissue-specific and implicated GPCR-encoding genes as potential mediators of the molecular adaptations to training.", + "metadata": { + "target": "external", + "tags": [ + "companion-paper-published" + ], + "icon": "auto_stories" + }, + "links": [ + { + "label": "Molecular adaptations in response to exercise training are associated with tissue-specific transcriptomic and epigenomic signatures", + "url": "https://doi.org/10.1016/j.xgen.2023.100421", + "gaEventCategory": "MoTrPAC Companion Paper", + "gaEventAction": "Cell Publication" + } + ] + }, + { + "aid": 8, + "posted_date": "2024-05-01", + "title": "MoTrPAC animal physiological adaptations study published in Function", + "content": "This paper extensively characterizes physiological adaptations to progressive endurance exercise in fully mature adult and aged rats, serving as a phenotypic compendium of the MoTrPAC pre-clinical animal endurance training data resource. Ultimately, the goal of this resource is to foster phenotypic and multi-omic data integration to develop an integrative molecular map of time-, sex-, and age-specific responses to endurance exercise training.", + "metadata": { + "target": "external", + "tags": [ + "companion-paper-published" + ], + "icon": "auto_stories" + }, + "links": [ + { + "label": "Physiological adaptations to progressive endurance exercise training in adult and aged rats: insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC)", + "url": "https://doi.org/10.1093/function/zqae014", + "gaEventCategory": "MoTrPAC Companion Paper", + "gaEventAction": "Function Publication" + } + ] + }, + { + "aid": 9, + "posted_date": "2024-05-01", + "title": "MoTrPAC animal white adipose tissue study published in Nature Metabolism", + "content": "Multi-omic profiling identifies profound sexual dimorphism in the subcutaneous white adipose tissue (scWAT) molecular landscape of sedentary rats that is largely preserved or amplified with training. Using a computational approach, we identify candidate molecular regulators of sexually dimorphic scWAT phenotypic responses to training, demonstrating the resource utility of MoTrPAC-generate data to drive novel hypothesis-based research in the field.", + "metadata": { + "target": "external", + "tags": [ + "companion-paper-published" + ], + "icon": "auto_stories" + }, + "links": [ + { + "label": "Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue", + "url": "https://doi.org/10.1038/s42255-023-00959-9", + "gaEventCategory": "MoTrPAC Companion Paper", + "gaEventAction": "Nature Publication" + } + ] + }, + { + "aid": 10, + "posted_date": "2024-05-01", + "title": "MoTrPAC animal endurance training study published in Nature", + "content": "The main MoTrPAC animal endurance training study has been published in Nature. This study profiled the temporal transcriptome, proteome, metabolome, lipidome, phosphoproteome, acetylproteome, ubiquitylproteome, epigenome, and immunome in whole blood, plasma, and 18 solid tissues in male and female rats over 8 weeks of endurance exercise training. The resulting data compendium encompasses 9466 assays across 19 tissues, 25 molecular platforms, and 4 training time points in young adult male and female rats.", + "metadata": { + "target": "external", + "tags": [ + "landscape-paper-published" + ], + "icon": "auto_stories" + }, + "links": [ + { + "label": "Temporal dynamics of the multi-omic response to endurance exercise training", + "url": "https://www.nature.com/articles/s41586-023-06877-w", + "gaEventCategory": "MoTrPAC Landscape Paper", + "gaEventAction": "Nature Publication" + }, + { + "label": "Explore the multi-omic analysis results presented in this published paper", + "url": "/graphical-clustering", + "gaEventCategory": "MoTrPAC Landscape Paper", + "gaEventAction": "Graphical Clustering" + } + ] } ] diff --git a/src/LandingPage/landingPage.jsx b/src/LandingPage/landingPage.jsx index 3ec9a976..aae8833b 100644 --- a/src/LandingPage/landingPage.jsx +++ b/src/LandingPage/landingPage.jsx @@ -9,6 +9,8 @@ import PromoteBanner from './promoteBanner'; import landingPageStructuredData from '../lib/searchStructuredData/landingPage'; import IconSet from '../lib/iconSet'; +import LogoMotrpacWhite from '../assets/logo-motrpac-white.png'; +import BackgroundVideoPreloader from '../assets/LandingPageGraphics/background_video_preload.jpg'; import LayerRunner from '../assets/LandingPageGraphics/Data_Layer_Runner.png'; import RatFigurePaass1b from '../assets/LandingPageGraphics/rat-figure-pass1b.svg'; import LandscapePreprintAbstract from '../assets/LandingPageGraphics/landscape_preprint_abstract.jpg'; @@ -137,7 +139,7 @@ let events = { * @returns {object} JSX representation of the landing page. */ export function LandingPage({ isAuthenticated, profile }) { - // Local state for managing particle animation + const [backgroundVideoLoaded, setBackgroundVideoLoaded] = useState(false); const [data, setData] = useState(figure4eData); const [networkNodes, setNetwortNodes] = useState([]); const iframeRef = useRef(null); @@ -159,10 +161,7 @@ export function LandingPage({ isAuthenticated, profile }) { }, [networkNodes]); const goToExternalLink = useCallback(() => { - window.open( - 'https://www.biorxiv.org/content/10.1101/2022.09.21.508770v3', - '_blank', - ); + window.open('https://www.nature.com/articles/s41586-023-06877-w', '_blank'); }, []); // Redirect authenticated users to protected route @@ -171,6 +170,13 @@ export function LandingPage({ isAuthenticated, profile }) { return- - Molecular Transducers of Physical Activity Consortium (MoTrPAC) - {' '} - is a national research consortium. Its goal is to{' '} - - study the molecular changes that occur in response to exercise, - {' '} - and ultimately to advance the understanding of how physical - activity improves and preserves health. We aim to generate a - molecular map of the effects of exercise. +
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