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Optimal Dose Escalation Methods using Deep Reinforcement Learning in Phase I Oncology Trials

Supplementary Materials for Kentaro Matsuura, Kentaro Sakamaki, Junya Honda, Takashi Sozu "Optimal Dose Escalation Methods using Deep Reinforcement Learning in Phase I Oncology Trials" Journal of Biopharmaceutical Statistics 2023; (doi:10.1080/10543406.2023.2170402)

We have released the R package on CRAN and GitHub. Please use the package to apply our method to actual clinical trials or simulation studies.